USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: CLIC4_HUMAN USC-OGP 2-DE database:  CLIC4_HUMAN CLIC4_HUMAN General information about the entry View entry in simple text format Entry name CLIC4_HUMAN Primary accession number Q9Y696 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Chloride intracellular channel protein 4; AltName: Full=Intracellular chloride ion channel protein p64H1;. Gene name Name=CLIC4 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0497: pI=5.21; Mw=29057 SPOT OGP-0500: pI=5.30; Mw=28252 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1093: pI=5.48; Mw=166149 Cross-references UniProtKB/Swiss-Prot Q9Y696; CLIC4_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name CLIC4_HUMAN Primary accession number Q9Y696 Secondary accession number(s) Q9UFW9 Q9UQJ6 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 161) Name and origin of the protein Description RecName: Full=Chloride intracellular channel protein 4; AltName: Full=Intracellular chloride ion channel protein p64H1; Gene name Name=CLIC4 Encoded on Name=CLIC4 Keywords 3D-structure; Acetylation; Cell junction; Cell membrane; Chloride; Chloride channel; Complete proteome; Cytoplasm; Cytoplasmic vesicle; Cytoskeleton; Direct protein sequencing; Ion channel; Ion transport; Membrane; Mitochondrion; Nucleus; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport; Voltage-gated channel. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF097330; AAD38446.1; -; mRNA EMBL AF109196; AAD26136.1; -; mRNA EMBL AL117424; CAB55916.1; -; mRNA EMBL BC012444; AAH12444.1; -; mRNA CCDS CCDS256.1; -; . PIR T17226; T17226; . RefSeq NP_039234.1; NM_013943.2; . UniGene Hs.440544; -; . PDB 2AHE; X-ray; 1.80 A; A=1-251 PDB 2D2Z; X-ray; 2.20 A; A/B/C=1-253 PDB 3OQS; X-ray; 2.00 A; B=198-207 PDBsum 2AHE; -; . PDBsum 2D2Z; -; . PDBsum 3OQS; -; . ProteinModelPortal Q9Y696; -; . SMR Q9Y696; -; . BioGrid 117431; 47; . IntAct Q9Y696; 5; . MINT MINT-3087884; -; . STRING 9606.ENSP00000363500; -; . TCDB 1.A.12.1.6; the intracellular chloride channel (clic) family; . iPTMnet Q9Y696; -; . PhosphoSitePlus Q9Y696; -; . SwissPalm Q9Y696; -; . BioMuta CLIC4; -; . DMDM 20141285; -; . OGP Q9Y696; -; . REPRODUCTION-2DPAGE IPI00001960; -; . EPD Q9Y696; -; . MaxQB Q9Y696; -; . PaxDb Q9Y696; -; . PeptideAtlas Q9Y696; -; . PRIDE Q9Y696; -; . TopDownProteomics Q9Y696; -; . DNASU 25932; -; . Ensembl ENST00000374379; ENSP00000363500; ENSG00000169504; . Ensembl ENST00000488683; ENSP00000436538; ENSG00000169504; . GeneID 25932; -; . KEGG hsa:25932; -; . UCSC uc001bjo.3; human; . CTD 25932; -; . DisGeNET 25932; -; . GeneCards CLIC4; -; . HGNC HGNC:13518; CLIC4; . HPA HPA008019; -; . HPA HPA060804; -; . MIM 606536; gene; . neXtProt NX_Q9Y696; -; . OpenTargets ENSG00000169504; -; . PharmGKB PA26591; -; . eggNOG KOG1422; Eukaryota; . eggNOG ENOG410ZRK6; LUCA; . GeneTree ENSGT00550000074477; -; . HOGENOM HOG000231548; -; . HOVERGEN HBG050994; -; . InParanoid Q9Y696; -; . KO K05024; -; . OMA IWKYLNN; -; . OrthoDB EOG091G0IHT; -; . PhylomeDB Q9Y696; -; . TreeFam TF315438; -; . ChiTaRS CLIC4; human; . EvolutionaryTrace Q9Y696; -; . GeneWiki CLIC4; -; . GenomeRNAi 25932; -; . PRO PR:Q9Y696; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000169504; -; . CleanEx HS_CLIC4; -; . ExpressionAtlas Q9Y696; baseline and differential; . Genevisible Q9Y696; HS; . GO GO:0015629; C:actin cytoskeleton; TAS:UniProtKB; . GO GO:0045177; C:apical part of cell; IDA:UniProtKB; . GO GO:0009986; C:cell surface; IDA:UniProtKB; . GO GO:0005911; C:cell-cell junction; IDA:UniProtKB; . GO GO:0005813; C:centrosome; IDA:UniProtKB; . GO GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005622; C:intracellular; IDA:LIFEdb; . GO GO:0005902; C:microvillus; IDA:UniProtKB; . GO GO:0030496; C:midbody; IDA:UniProtKB; . GO GO:0005739; C:mitochondrion; IDA:UniProtKB; . GO GO:0016363; C:nuclear matrix; IDA:UniProtKB; . GO GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB; . GO GO:0005886; C:plasma membrane; IDA:UniProtKB; . GO GO:0005254; F:chloride channel activity; TAS:ProtInc; . GO GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW; . GO GO:0001525; P:angiogenesis; IEA:Ensembl; . GO GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl; . GO GO:0030154; P:cell differentiation; TAS:UniProtKB; . GO GO:0071277; P:cellular response to calcium ion; IMP:UniProtKB; . GO GO:0006821; P:chloride transport; NAS:UniProtKB; . GO GO:0001886; P:endothelial cell morphogenesis; IEA:Ensembl; . GO GO:0035088; P:establishment or maintenance of apical/basal cell polarity; NAS:UniProtKB; . GO GO:0009566; P:fertilization; IEA:Ensembl; . GO GO:0030216; P:keratinocyte differentiation; IMP:UniProtKB; . GO GO:0035264; P:multicellular organism growth; IEA:Ensembl; . GO GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB; . GO GO:0051493; P:regulation of cytoskeleton organization; NAS:UniProtKB; . GO GO:0061299; P:retina vasculature morphogenesis in camera-type eye; IEA:Ensembl; . GO GO:0007035; P:vacuolar acidification; IEA:Ensembl; . Gene3D 1.20.1050.10; -; 1; . Gene3D 3.40.30.10; -; 1; . InterPro IPR002946; CLIC; . InterPro IPR010987; Glutathione-S-Trfase_C-like; . InterPro IPR012336; Thioredoxin-like_fold; . PRINTS PR01263; INTCLCHANNEL; . SFLD SFLDG01175; Main.10_; 1; . SUPFAM SSF47616; SSF47616; 1; . SUPFAM SSF52833; SSF52833; 1; . TIGRFAMs TIGR00862; O-ClC; 1; . PROSITE PS50405; GST_CTER; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
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• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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